Compounds
Synthetic pentadecapeptide · sequence derived from a protein found in human gastric juice
The most-studied compound in this catalogue by volume of papers, and the one where
the gap between reputation and evidence is widest. Research has examined tissue
repair — tendon, ligament, muscle and gut mucosa — and protection against
NSAID-induced gastrointestinal lesions, almost entirely in rats and mice.
The great majority of that work originates from a single group in Zagreb led by
Predrag Sikirić, published over roughly three decades. Independent replication
outside that group is limited, and no completed human clinical trial has
been published. Enthusiasm for this compound online substantially
outruns what the literature supports.
- Studied inRodent models — tendon, gut, muscle
- Human trialsNone published
- WADA statusProhibited (S0, at all times)
- StabilityLyophilised, stable at -20°C
Synthetic fragment corresponding to a region of Thymosin Beta-4
Thymosin Beta-4 is a naturally occurring actin-sequestering protein with a genuine
research literature in cell migration, angiogenesis and wound repair. TB-500 is a
shorter synthetic fragment, and studies of the two are frequently — and
incorrectly — treated as interchangeable.
Full-length TB-4 has been through early human trials for corneal and dermal wound
healing. The fragment sold as TB-500 has not, and the evidence base attributed to
it is largely borrowed from work on the parent protein.
- Studied inCell culture, rodent wound models
- Human trialsParent protein only, not the fragment
- WADA statusProhibited (S2)
- StabilityLyophilised, stable at -20°C
CJC-1295 / MOD GRF (1-29)
Human data
Analogue of growth hormone releasing hormone, GHRH(1-29)
Investigated for its effect on growth hormone and IGF-1 secretion. Human
pharmacokinetic work exists — notably a 2006 study in the Journal of Clinical
Endocrinology & Metabolism examining dose-dependent GH and IGF-1 elevation in
healthy adults.
A naming warning that matters when buying. "CJC-1295" properly
refers to the version carrying a Drug Affinity Complex, which greatly extends
half-life. "MOD GRF (1-29)" is the modified peptide without it. The two are
routinely sold under each other's names across this industry. Check the mass on
the certificate, not the label on the site.
- Studied inHealthy human volunteers, rodents
- Human trialsYes — early phase, published
- WADA statusProhibited (S2)
- StabilityLyophilised, stable at -20°C
Pentapeptide · selective growth hormone secretagogue receptor agonist
Developed at Novo Nordisk and characterised in the late 1990s as a selective GH
secretagogue — releasing growth hormone with markedly less effect on cortisol and
prolactin than earlier compounds in its class, which is why it appears so often in
the literature as a research tool.
It progressed to human clinical trials for post-operative ileus. Those trials did
not meet their endpoints and development was discontinued — a fact worth knowing,
since the compound is frequently marketed as though its clinical history were a
success rather than a stopped programme.
- Studied inHuman trials, rodent and canine models
- Human trialsYes — discontinued after phase 2
- WADA statusProhibited (S2)
- StabilityLyophilised, stable at -20°C
GHRH(1-29) · the shortest fully active fragment of growth hormone releasing hormone
The strongest regulatory history in this catalogue. Sermorelin was approved as a
prescription medicine in the United States under the name Geref and used in
assessing growth hormone deficiency in children. It was withdrawn from that market
in 2008 for commercial rather than safety reasons.
Because it went through formal approval, its pharmacology, dosing behaviour and
adverse-event profile are documented to a standard nothing else on this page
approaches.
- Studied inHuman clinical trials, paediatric and adult
- Human trialsYes — reached market approval
- WADA statusProhibited (S2)
- StabilityLyophilised, stable at -20°C
Copper-binding tripeptide · glycyl-L-histidyl-L-lysine, naturally present in human plasma
Unusual here in being both naturally occurring and commercially established. GHK
was identified in human plasma in the 1970s; its concentration declines
substantially with age. Research has examined copper transport, collagen and
glycosaminoglycan synthesis, and dermal wound repair, with much of the foundational
work by Loren Pickart.
It is widely used as a cosmetic ingredient in topical formulations, which means
human skin-level data exists in a way it does not for most peptides sold as
research chemicals.
- Studied inHuman skin studies, cell culture, rodents
- Human trialsYes — topical/dermatological
- WADA statusNot prohibited
- StabilityLyophilised; blue tint is the copper complex, not contamination
Thymosin Alpha-1
Clinical
28-amino-acid peptide · immunomodulator, naturally produced by the thymus
An approved medicine in a number of countries, marketed as thymalfasin, with a
clinical literature spanning chronic hepatitis B and C, immune reconstitution and
adjunct use in sepsis. It has been the subject of randomised controlled trials —
genuinely rare in this catalogue.
Because it is a licensed medicine in several jurisdictions, its regulatory position
is more complex than the rest of this list, and it is supplied here strictly as a
research reference material.
- Studied inRandomised controlled human trials
- Human trialsYes — approved medicine in several countries
- WADA statusNot prohibited
- StabilityLyophilised, stable at -20°C
Synthetic tetrapeptide · Ala-Glu-Asp-Gly
Included with an explicit warning. Epitalon originates from work on pineal peptide
preparations by Vladimir Khavinson's group in St Petersburg, examining telomerase
activity and lifespan in cell culture and rodents.
The evidence is weak. Studies are small, overwhelmingly from one
group, largely published in journals with limited international reach, and not
independently replicated at any scale. The extraordinary longevity claims made for
this compound online are not supported by anything we would call reliable data. We
supply it because it is a legitimate research material and researchers ask for it —
not because we think the case for it is made.
- Studied inCell culture, rodents — single group
- Human trialsLimited, not independently replicated
- WADA statusNot listed
- StabilityLyophilised, stable at -20°C